منابع مشابه
Plasticity to the Rescue
The balance between excitatory and inhibitory inputs is critical for the proper functioning of neural circuits. Landau and colleagues show that, in the presence of cell-type-specific connectivity, this balance is difficult to achieve without either synaptic plasticity or spike-frequency adaptation to fine-tune the connection strengths.
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Population persistence in a new and stressful environment can be influenced by the plastic phenotypic responses of individuals to this environment, and by the genetic evolution of plasticity itself. This process has recently been investigated theoretically, but testing the quantitative predictions in the wild is challenging because (i) there are usually not enough population replicates to deal ...
متن کاملGenetic rescue to the rescue.
Genetic rescue can increase the fitness of small, imperiled populations via immigration. A suite of studies from the past decade highlights the value of genetic rescue in increasing population fitness. Nonetheless, genetic rescue has not been widely applied to conserve many of the threatened populations that it could benefit. In this review, we highlight recent studies of genetic rescue and pla...
متن کاملCLIPs to the rescue
Suicide attempt linked to breakdown he Golgi apparatus breaks down temporarily to segregate into daughter cells during mitosis, but during apoptosis the organelle fragments irreversibly. On page 637, Chiu et al. report that cleavage of a critical tethering protein during apoptosis not only drives the fragmentation of the Golgi apparatus, but also appears to help propagate the apoptotic signal. ...
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ژورنال
عنوان ژورنال: Neuron
سال: 2016
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2016.11.042